At Maine, Koneshan worked on ion transport in bulk water, at ambient and supercritical temperatures, with Rasaiah and post-doctoral Dr. Peter Norywotna. Other members of the group are graduate students A. Waghe (Chemistry) and S. Vaitheeswaran (Physics). Professor Rasaiah and Ruth Lynden-Bell (Queen's University, Belfast) also work on ion transport, but in smooth channels. The interdisciplinary group's various projects are supported by the NSF.

Koneshan (center in the photo) is shown with Cornell Professors Jon Kleinberg (left) and Ron Elber (right) of the Computer Science department. These two faculty, along with Professor David Shalloway of Molecular Biology and Genetics, Harold Scheraga (Chemistry and Chemical Biology), David Shmoys (Industrial Engineering and Computer Science), Benoit Roux (Biochemistry and Structural Biology), and Rasmus Nielsen (Biometrics) form the loosely defined "computational molecular biology group" at Cornell.
Koneshan is modeling how ions are transported through channels in the walls of cells.

In the graphic above, a sodium ion (the small pink sphere in the center) is shown moving through such a channel.