PATENTS IN THE FIELD OBTAINED BASED ON OUR PUBLISHED WORK

“A systematic treatment of chemical equilibria is used to determine the average molecular weight of the Suwannee River fulvic acids directly from aqueous solutions. Additionally, parameters such as equilibrium constant and reaction stoichiometry can be calculated. The measurement of the initial mass of unknown analytes is not needed for the determination”

http://www.patentstorm.us/patents/6745132.html

"Solouki and Russell (T. Solouki, D. Russell, Proc. Natl. Acad. Sci. USA 89, 5701(1992)) have demonstrated effective trapping of high kinetic energy ions by using a collisional cooling process used in conjunction with a high trapping voltage. In these studies, MALDI ions were cooled through collisions with inert gas molecules in a small volume chamber before entering the FTMS cell. An electrostatic wire ion guide was also used to position ions along the exact center of the cell. In this way, ions up to 157,000 Da were trapped and detected (T. Solouki, K. J. Gilling, D. H. Russell, Anal. Chem. 66, 1583(1994)). However, mass resolution was low."

http://www.freepatentsonline.com/6130426.html

"The magnitude of the potentials placed on the trapping electrodes is significant both to the degree to which the cyclotron motion is distorted and to the range of the kinetic energy that an ion can have along the magnetic field lines and still be trapped. The kinetic energy of the ions which can be trapped is directly related to the potential on the trapping electrodes and so is the distortion on the cyclotron motion. Thus, in a prior art FTICR cell, the potential on the trapping electrodes would be set as a compromise between trapable ion kinetic energy and distortion in cyclotron motion. The trapping potential must be kept low (e.g. 1V) to avoid excessive cyclotron motion, and as a result, the range of trapable ion kinetic energies is also low (e.g. 1 eV). This limits the FTMS method in its application to external ion sources because such sources often produce ion beams which have a broad range of kinetic energies (R. C. Beavis, B. T. Chait, Chem. Phy. Lett. 181, 479(1991), T.-W. D. Chan et al., Chem. Phy. Lett. 222, 579(1994), J. A. Castoro, C. Koester, C. L. Wilkins, Rapid Commun. Mass Spectrom. 6, 239(1992), C. Koester, J. A. Castoro, C. L. Wilkins, J. Am. Chem. Soc. 114, 7572(1992), J. Yao, M. Dey, S. J. Pastor, C. L. Wilkins, Anal. Chem. 67, 3638(1995), T. Solouki, D. H. Russel, Proc. Natl. Acad. Sci. USA 89, 5701(1992), T. Solouki, K. J. Gilling, D. H. Russel, Anal. Chem. 66, 1583(1994)). "

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